Laughs 4 Life returns for a tenth year with a night of comedy featuring Greg Warren and special guests Maggie Hughes DePalo and Mason James at the historic Saenger Theater in Downtown Hattiesburg Saturday, August 8, 2026. Laughs 4 Life, in partnership with the Pinebelt Foundation, will once again benefit The International Myeloma Foundation, the Forrest General Hospital Cancer Center, and Children's of Mississippi. This year we will also support the Cancer Center and Research Institute at the University of Mississippi.